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Spencer Smythe

First Appearance: The Spider Slayer
Voice: Edward Mulhare
Spencer Smythe was the man who originally designed the Spider Slayers. He designed them for Norman Osborne who was working for The Kingpin. Hoping that once Spider-Man has been captured, Norman would create a new chair in which his paralyzed son, Alistair would be more comfortable with.

After the slayer caught the wrong person, Spider-Man and the first Spider Slayer, the Black Widow fought in Oscorp, which exploded, leading everyone to believe, Spencer, who was trapped inside, had died.

This wasn't the case; the Kingpin had him frozen in order to convince Alistair to work for him. Once Alistair discovered the truth, he began devoting his full attention into reviving his father.